The CLOtest Rapid Urease Test (RUT) accurately and conveniently detects the urease enzyme of Helicobacter pylori in gastric mucosal biopsies. Its use is intended for the presumptive diagnosis of H. pylori infection.
CLOtest* is a well of urease indicator gel sealed inside a plastic slide. The gel contains urea, USP (29 mg/mL) phenol red (a pH indicator), buffers and a bacteriostatic agent to prevent the growth of contaminating urease-positive organisms. If the urease from H.pylori is present in the tissue sample, it changes the gel from yellow to bright magenta.